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Neural stem cells, brain organoids and brain repair
Additional Organiser: Society for Neuroscience (SfN)
Attendance type(s): In Person
FENS members will benefit from preferential rates
Event Dates: 03—9 Jun 2018
Human brain disorders have been challenging to understand at the molecular and cellular level due to lack of access to functioning tissue from patients. Neural stem cells derived from patients hold promise in modeling aspects of human brain development and disease non-invasively, in a dish. Moreover, three-dimensional (3D) cultures called brain organoids can be derived from induced pluripotent stem cells (hiPS cells) in an effort to mimic human brain development and to study cell-cell interactions, maturation and the mechanisms of disease.
In this school, we will discuss the properties of neural stem cells and ways to derive, differentiate and maintain them in vitro. We will provide an overview of the approaches for deriving 3D brain cultures and consider how this technology may inform the way we study neuropsychiatric disease. Lastly, we will explore ways in which neural stem cells can be used for therapeutic purposes and derive brain repair strategies.