The Brain Prize 2019 awarded

The Lundbeck Foundation Brain Prize announces that The Brain Prize 2019 is awarded to four French neuroscientists – Professor Marie-Germaine Bousser,Professor Hugues Chabriat,Dr Anne Joutel andProfessor Elisabeth Tournier-Lasserve – fortheir outstanding research related to the most common hereditary form of stroke, CADASIL (Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy).

The four scientists are being awarded The Brain Prize, worth 1 million euros, for their comprehensive, in-depth and relentless research efforts. Together, they have solved the puzzle and shown that CADASIL is a hereditary disease, caused by a mutation in the NOTCH3 gene on chromosome 19. Mutations in this gene result in an accumulation of protein in the walls of the small blood vessels and the children of mutation carriers have a 50% risk of inheriting it. The team has developed a diagnostic test and is involved in testing a potential treatment in animal models.  

Access the full press release, please visit The Brain Prize website.