Professor Tara Spires-Jones, PhD
Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK
Tara Spires-Jones obtained her PhD in Neuroscience from the University of Oxford. Prior to moving to Scotland in 2013, she ran a group studying Alzheimer’s disease pathogenesis with an emphasis on synaptic pathology at Massachusetts General Hospital (MGH) and Harvard Medical School, where she was an instructor from 2006-2011 and Assistant Professor from 2011-2013. Currently, she is a Professor of Neurodegeneration at the University of Edinburgh. Her research focuses on the mechanisms and reversibility of synapse degeneration in Alzheimer’s disease, other degenerative brain diseases, and ageing. Her work has shown that both of the proteins involved in the neuropathological lesions in Alzheimer’s disease (amyloid beta and tau) contribute to synapse degeneration, and further that reducing the levels of these proteins prevents degeneration and improves memory in disease models.