Job ID: 99954

Open PhD student position in the Stroke Laboratory, Lausanne University Hospital (CHUV) within the ERA-NET Neuron consortium

Position: Ph.D. Student

Deadline: 22 January 2023

City: Lausanne

Country: Switzerland

Institution: CHUV & UNIL Lausanne, Switzerland

Department:

Description:

We are offering an exciting PhD position linking the field of the gut-brain axis with stroke research within the newly funded consortium “BiotaBrainBarrier – Modulation of brain barrier function by microbiota-derived factors in cerebral ischemia”. The candidate will be hosted by the Hirt Lab (Lausanne, Switzerland) and collaborate closely with the two other consortium partners, the Benakis Lab (Munich, Germany) and the Mustafaoglou Lab (Istanbul, Turkey),

Job Description
The candidate will investigate the role of metabolites produced by the gut microbiota in the regulation of the blood-brain barrier and in the neurovascular unit damage following ischemic stroke. Research will involve microsurgery in rodents, evaluation of stroke outcome by behavioral and immunohistochemistry analyses and investigation of blood-brain barrier dynamics in collaboration with the two other consortium laboratories and researchers involved in the ongoing translational clinical trial in the CHUV to develop new therapies targeting the microbiota-brain axis to improve recovery of stroke patients.

Your profile:
We are looking for a PhD candidate with a Master’s degree in Neuroscience, Biology, Immunology or a related subject, who is interested in joining a team of dynamic scientists to work on experimental stroke and gut-brain axis research. The position is offered from April 1 2023 for 3 years.

Excellent oral and writing ability of English is essential, as the working language in the lab and within the consortium is English. We are particularly interested in an enthusiastic and critical-thinking candidate who works well in a team and is willing to travel to and sometimes work in the other consortium labs.

Experience with one or more of the following areas would be very useful: mouse handling (FELASA certificate) and surgery, confocal microscopy, knowledge in bioinformatics and programming languages (Python, R), and microbiology.

Your workplace
The Stroke Laboratory is part of a comprehensive Stroke Center in the Department of Clinical Neurosciences at the highly rated Lausanne University Hospital (CHUV), and hosted by the Department of Fundamental Neurosciences at the University of Lausanne, providing an outstanding scientific research environment. We offer a highly collaborative, interdisciplinary and international environment, using a broad array of methodologies including animal models, primary cell cultures, confocal imaging and molecular biology. You will be enrolled in the Lemanic Neuroscience Doctoral School (LNDS) of the Universities of Lausanne and Geneva,

Equal opportunity employer statement

The CHUV is an Equal Opportunities Employer and is committed to equal employment opportunities.

Interested in joining us? Please submit your CV/resume including job-related skills and list of publications, two letters of reference and a one-page statement of research interests to Prof. Lorenz Hirt (Lorenz.Hirt@chuv.ch). All applications must be submitted by e-mail by January 22nd, 2023.