Job ID: 99447

PhD student Molecular Cell Biology

Position: Ph.D. Student

Deadline: 15 February 2023

Employment Start Date: 3 April 2023

Contract Length: 3 years

City: Münster

Country: Germany

Institution: University of Münster

Department: Institute for Integrative Cell Biology and Physiology

Description:

The Institute for Integrative Cell Biology and Physiology at the University of Münster is looking for a PhD student (TVL-13 65%) to investigate the regulation of intracellular transport and exocytosis during neuronal differentiation.

The polarized transport and exocytosis of vesicles is essential to establish and maintain the complex architecture of the mammalian neocortex. Defects in these processes disrupt cortical development and lead to neurodevelopmental disorders and neurodegenerative diseases. We are investigating how the transport and exocytosis of vesicles are regulated during neuronal differentiation to facilitate axon growth. The project focuses on the functional analysis of GTPases and their regulators in primary cultures of neurons. It includes the development of genetically encoded sensors to analyze intracellular transport and membrane dynamics by live cell imaging.

We are looking for highly motivated candidates with an interest in understanding fundamental questions of neurobiology at the molecular and cellular level. A Master’s degree (or equivalent) in life or natural sciences is required. The project will employ a combination of molecular, cell biological, and genetic techniques in combination with life cell imaging to study differentiation in cultured neurons. Experience in molecular biology, life cell imaging or the culture of neurons is an advantage but not required.

The position is available initially for 3 years starting at the earliest possible date.

We offer an international environment with English as the language spoken in the lab (https://www.uni-muenster.de/Biologie.IMZ/pueschel/). The project will be embedded in graduate program with excellent supervision and a dynamic and international community of PhD students.

The University of Münster strongly supports equal opportunity and diversity. We welcome all applicants regardless of gender, nationality, ethnic or social background, religion, disability, age, sexual orientation or gender identity. The University of Münster is an equal opportunity employer and is committed to increasing the proportion of women academics. Consequently, we actively encourage applications by women. Female candidates with equivalent qualifications and academic achievements will be preferentially considered within the framework of the legal possibilities.

Applications (including CV, a brief summary of the Master’s project and Transcript of Records) should be sent to apuschel@uni-muenster.de