Job ID: 99274
Post Doc Position – Cellular Reprogramming for Glioblastoma Gene Therapy
Position: Post-doctoral Position
Deadline: 4 January 2023
Employment Start Date: 1 February 2023
Contract Length: 3 years
City: Lund
Country: Sweden
Institution: Lund University
Department: Clinical Sciences, Neurology, Lund Stem Cell Center
Description:
Cellular Reprogramming for Glioblastoma Gene Therapy
Lund Stem Cell Center is an internationally ranked research center in the strategic areas of Stem Cell Biology and Regenerative Medicine within Lund University, Scandinavia’s largest institution for education and research. The Lund Stem Cell Center is a strong international research center with a focus on stem cell and developmental biology of the central nervous system and blood system, development of stem cell and cell replacement therapies in these organ systems, as well as research in non-mammalian model systems.
One post doc position is available in the Stem Cells, Aging and Neurodegeneration group in collaboration with the Glioma Cell Therapy group. For more information on Lund Stem Cell Center and the group please visit:
www.stemcellcenter.lu.se/research-groups/ahlenius
https://www.stemcellcenter.lu.se/research-groups/bengzon
We are using stem cell, reprogramming and genome engineering technologies to develop models and novel therapeutics for brain disorders.
In this project the candidate will further develop our recent finding that glioblastoma cells can be reprogrammed to astrocyte like cells. The project will contain vector design, in vitro and in vivo reprogramming as well as work with tumor organoids and slice cultures. The main purpose of the project is to develop reprogramming as a gene therapy for glioblastoma with a clear goal of going to clinical trials.
We are looking for excellent, highly motivated, recently graduated (within 3 years) top- level PhDs with a strong background from molecular biology-, oncology-, reprogramming- and/or neurobiology fields. Hands on experience working with gene therapy approaches, viral vectors and sterotactic intracerebral injections, or reprogramming is meriting.
We offer the opportunity to be part of cutting-edge research and a vibrant scientific community, at an internationally renowned stem cell center.
The position is for 3 years. Tentative starting date is early 2023 but flexible. Apply before January 4th 2023 using the following link:
https://lu.varbi.com/en/what:job/jobID:575129/type:job/where:4/apply:1