Job ID: 99026

Head of IPSC platform

Position: Scientist

Deadline: 3 January 2023

Employment Start Date: 1 March 2023

Contract Length: 1 year renewable

City: Prilly

Country: Switzerland

Institution: centre hospitalier universitaire Vaudois

Department:

Description:

We are looking for a Head of the iPSC platform at the center for psychiatric neuroscience.

Missions

  • Conduct and participate to the generation of IPSC lines
  • Ensure the proper functioning of the biobank
  • Establish biological techniques to generate and characterize IPSCs within the framework of service projects
  • Support, train and supervise the staff and users of the platform
  • Conduct the administrative part (consumables management, orders, pricing of services to users, operational organization…)
  • Ensure scientific and technological monitoring in relation to the platform’s activities
  • Write procedures and reports
  • Lead committees or seminars to participate in the development of the platform
  • Participate in research projects involving the platform.

Profile

  • Engineer or PhD in Cellular and/or Molecular Biology
  • At least 2-3 years experience in IPSC culture
  • Experience working in a platform, as well as knowledge of cell imaging are a plus.

Context 

The Centre Hospitalier Universitaire Vaudois (CHUV) is the largest employer in the canton of Vaud with more than 12,000 employees and where more than 113 nationalities are represented. The CHUV is internationally recognized as one of the best hospitals in the world, taking ninth place in the ranking score in 2021. Thanks to its close collaborations with the University of Lausanne, the Faculty of Biology and Medicine, and other leading academic institutions such as EPFL, the CHUV enjoys a leading role in the fields of care, training and medical research.

Its location is an integral part of its assets, since it is located in the heart of the charming city of Lausanne, a cosmopolitan city known to be the Olympic headquarters and on the shores of Lake Geneva, one of the most beautiful lakes in Europe.

The Centre for Psychiatric Neurosciences (CNP) is part of the CHUV’s Psychiatry department and is located within the hospital complex of Cery, situated in an exceptional green setting in the city of Prilly (Western Lausanne). The CNP created to promote the translational research in Psychiatric Neuroscience bringing together both researchers and clinicians. A dedicated building of 2500m2 spread over 5 levels was inaugurated at the end of 2018. The center benefits of the state-of-the-art equipment shared by a dozen research teams working in close collaboration with clinicians. Several cohorts of patients with major psychiatric disorders, such as severe depression, bipolar illness and schizophrenia, and their at-risk children have been recruited over 20 years at the DP-CHUV. These cohorts, for which the participants have been finely evaluated from a clinical point of view, are quite unique internationally and are already involved in various translational research projects, which aim in particular to better understand the pathophysiology of these major psychiatric disorders.

In order to broaden the scope of its translational research, the CNP has launched a vigorous initiative to significantly increase its capacity to generate induced pluripotent stem cells (iPSCs), in particular from these quite unique cohorts, through the creation of a dedicated platform. These iPSCs, notably through the process of neurodifferentiation, will be used as an in vitro model of these major psychiatric disorders in order not only to better understand their pathogenesis, but also to identify biomarkers to help in diagnosis and/or management (personalized medicine). Currently, this position of cell platform head is open for application.

The candidate will manage the production of the IPSC while leading the operational and technological activities of the platform.

Contact person in case of questions about this role : Dr. Carine Ben Adiba at +41213149328.

All of our applications are processed electronically.

For this reason, we kindly ask you to apply exclusively by applying directly toward this link :

Head of IPSC / Responsable de la Plateforme de Cellules IPSC (09174-RE-230-2022) (chuv.ch)

The CHUV applies the highest quality requirements as part of its recruitment process. In addition, mindful to promote workplace diversity and inclusion we strive to ensure equal treatment and avoid any discrimination. We are looking forward to receiving your application.

We would like to inform external recruitment agencies that any application inserted directly on our recruitment platform won’t be accepted and cannot be charged. Thank you for your understanding.