Job ID: 96046

Postdoc or research associate for transcriptomic profiling in motor neurophysiology

Position: Post-doctoral Position

Deadline: 31 October 2022

Employment Start Date: 1 January 2023

Contract Length: Initial 2-year contract, with the possibility for extension.

City: Saclay

Country: France

Institution: CNRS

Department: Paris-Saclay Institute of Neuroscience

Description:

A fully-funded position is available to work on the neuronal control of movements, with a focus on brainstem and spinal cord circuits for locomotion and body movements. With the support of ANR and FRM grants, you will in particular investigate the diversity of specific brainstem and spinal neuronal neurons from the connectomics and gene expression standpoints, combining mouse genetics, viral synaptic tracings, high-throughput single-nucleus profiling, and anatomical reconstructions.

The contract is for at least 2 full years, with a possibility for extension.

You will be joining a dynamic team of neurophysiologists with recognized expertise in deciphering the organization of motor circuits using multiple anatomical, genetic and functional approaches. You will have access to state-of-the-art viral tools, transgenic mice lines, and core facilities for sequencing and imaging.

You will evolve in the stimulating and international environment of the NeuroPSI institute, dedicated to studying brain function from genes to artificial intelligence. Our lab just moved to a brand-new building at the heart of the multi-disciplinary scientific park of Paris-Saclay.

The ideal candidate holds a PhD, should be interested in brainstem and spinal motor circuits and has some of the following qualifications:

  • Molecular biology including tissue dissociation and FACS sorting;
  • RNA sequencing and genomic data analysis ideally at the single cell or single nucleus level;
  • Be genuinely motivated, have excellent communication skills, and be sensible to a healthy and constructive team-spirit.
  • Minimal computer literacy, including Seurat, Matlab, R, or python will be a valuable asset;
  • Interest in learning experimental approaches on transgenic mice including surgical procedures and viral tools.

Interested candidates should send to Julien Bouvier:

  • a 2-page statement of interest, summarizing your past work and interest in our team and projects;
  • a detailed CV
  • at least 2 references.