Job ID: 87018
Postdoctoral Research Scientist in Striatal Neuromodulation in Parkinson’s Disease
Position: Post-doctoral Position
Deadline: 27 September 2022
Employment Start Date: 1 November 2022
Contract Length: 2 years in the first instance
City: Oxford
Country: United Kingdom
Institution: University of Oxford
Department: Department of Physiology, Anatomy and Genetics
Description:
The Cragg Group at the University of Oxford have received a major funding award from the Aligning Science Across Parkinson’s (ASAP) Initiative (https://parkinsonsroadmap.org/) for a multi-centre team for collaborative research into the neuroscience of Parkinson’s disease. The team is part of a global ASAP-funded network of scientists, a multidisciplinary effort to transform research into Parkinson’s by promoting open and collaborative science at all stages of discovery. We are now seeking to appoint two Postdoctoral Research Scientists to work as part of this exciting collaboration.
The successful candidates will become members of the Cragg group and will undertake studies to identify the neural circuits that act on dopamine axons to regulate dopamine transmission in health and its demise in mouse models of the disease. The postholders will interact closely with our collaborators in Oxford, Boston and Sweden, in order to better define the key modulatory circuits involved through a range of approaches. These post-holders will focus on studying dopamine neurotransmission using real-time methods like fast-scan cyclic voltammetry, electrophysiology, and imaging of genetically encoded fluorescent reporters, in brain slices in mouse models of Parkinson’s disease. They will also train and supervise other members of the team. The candidates will be responsible for conducting, analyzing and interpreting scientific data generated from experiments, and curating high quality data and protocols for sharing with our collaborators and the ASAP hub.
In addition to having, or nearing completion of, a PhD/M.D. or equivalent qualification in a relevant discipline, candidates should ideally have a promising track record of original research in their particular field of neuroscience. Candidates would ideally have technical expertise in recordings in acute brain slices using electrophysiology, electrochemistry or imaging, in neurosurgery in rodents.
The postholders will work in the Group led by Professor Stephanie Cragg, and will be based at the Department of Physiology, Anatomy and Genetics, Sherrington Building, Parks Road, Oxford, OX1 3PT.
The post is available immediately although start date is flexible, and the post is fixed-term until 31/10/2024 in the first instance.
Informal enquiries about the project can be addressed to Stephanie.cragg@dpag.ox.ac.uk.
Closing date for applications is midday on Tuesday 27th September.
A link to the Job Description and Application Portal can be found here.
Interviews are likely to be held in mid October.