Job ID: 84510

Post-Doc Position in Cell Biology/Neurosciences- Lineage reprogramming

Position: Post-doctoral Position

Deadline: 31 August 2022

Employment Start Date: 1 October 2022

Contract Length: 2 years (extendable)

City: LYON

Country: France

Institution: Stem Cell and Brain Research Institute (SBRI)

Department: Cellular Reprogramming and Brain Repair

Description:

Project: Interested in direct lineage reprogramming of glial cells into induced neurons as a novel cell-based strategy for brain repair? Join a collaborative project to decipher the molecular programs of direct reprogramming in the framework of LabEx (Laboratory of Excellence) CORTEX between Christophe Heinrich (SBRI, Team: Cellular Reprogramming and Brain Repair), Mirjam Zeisel (CRCL, Team: Epigenetics, Microenvironment and Liver Cancer) & Julien Courchet (INMG, Team: Energy Metabolism and Neuronal Development). You will be working at the interface of neurosciences, cell biology, transcriptomics, and epigenetics. For more background, see Heinrich, Nature Cell Biol 2015; Courchet, Nat Commun, 2018; Vignoles, Trends Mol Med 2019; Hamdane, Gastroenterology 2019; Jühling, Gut 2021; Lentini, Cell Stem Cell 2021.

Environment: You will join a multidisciplinary team of scientists. The institutes benefit from state-of-the-art research platforms including Omics and Imaging, and provide a high-quality scientific, technological and medical environment.

Candidates: We are looking for an enthusiastic, interactive and highly motivated scientist holding a PhD and willing to join a challenging research area. Applicants are expected to have a strong background and proven track record in cell biology or neurosciences. Experience in working with cellular/molecular biology, scRNA-Seq, and/or ChiP-Seq will be valuable. Expertise in sequencing data analysis would be helpful. English proficiency is mandatory (French is a plus). Strong communication skills, team spirit and ability to work in a multidisciplinary team are expected.

Location:

Stem Cell and Brain Research Institute (SBRI)-INSERM U1208-Lyon, France

Centre de Recherche en Cancérologie de Lyon (CRCL)-INSERM U1052 – CNRS 5286-CLB-Lyon, France

Application: Please send one PDF file to:

Christophe Heinrich (christophe.heinrich at inserm.fr)

Mirjam Zeisel (mirjam.zeisel at inserm.fr)

containing the following:

–Curriculum Vitae including publication list and contact details of 2-3 referees

-Cover letter with short statement of the research interests

-Concise summary of previous research activities (max 1 page)