Job ID: 100393
Postdoctoral fellowship focussed on experimental Parkinson’s disease
Position: Post-doctoral Position
Deadline: 31 March 2023
Employment Start Date: 1 May 2023
Contract Length: 2-4 years
Institution: Lund University
Department: Clinical Sciences
Do you want to solve clinically relevant research questions?
We are seeking a highly skilled and enthusiastic post-doctoral research fellow to join our translational research team at Lund University in Sweden.
This is an exciting opportunity to be involved in a preclinical research project investigating microvascular and blood-brain barrier changes in Parkinson’s disease on a cellular and molecular level, elucidating the triggering factors, identifying novel target molecules and investigating the impact of several clinically relevant treatments.
Bridging the lab and the clinic, in the “Translational Neurology Group” led by Prof Gesine Paul-Visse, we are interested in cutting-edge neuroregenerative therapies spanning from mechanistic studies for target identification all the way to clinical trials. We particularly examine the dysfunction of the neurovascular unit with a special focus on pericytes, gatekeepers at the blood/brain-interface and key players in inflammation and neurodegeneration, as potential target cells for brain repair. Our research is translational, involves human samples and has a close connection to clinical implementation.
Our lab is embedded in close collaborations and has access to core facilities of centres of excellence in neurodegenerative disease research (www.med.lu.se/multipark) and regeneration (www.wcmm.lu.se).
Lund University is a dynamic environment for junior researchers and provides excellent post-doctoral training in state-of –the art techniques, numerous guest lectures and workshops.
We are looking for a highly motivated and skilled person to drive a project focussed on the characterization of vascular cells in models of Parkinson’s disease. This project is based on recent findings from our group (PMID: 35360216 ; PMID: 36448982; PMID: 34376193 ; PMID: 33441868). You will work with rodent in vivo models, stereotaxic surgery, confocal and light sheet imaging, single cell RNA-sequencing and proteome analysis as well as analysis of human samples.
You will be fully integrated in our research group, have access to the necessary core facilities and participate in journal clubs, lab meetings and seminars.
We offer a full time (100%) postdoctoral training fellowship for 2-4 years, starting in 2023. You will be part of a team and use cutting edge technologies such as single cell RNA-sequencing or proteomics, and you will advance knowledge to slow disease progression in Parkinson’s disease and other neurodegenerative disorders. We offer an inspiring, interactive and international research environment, excellent training possibilities and an outstanding research network.
Are you the right person for this position?
You are a PhD about to defend your thesis or a Postdoc with a PhD preferably no longer than 3 years back at the time you start your position.
You have previous experience in working with one or more of the following: rodent models of Parkinson’s disease, stereotaxic surgery, vascular biology, molecular biology, immunohistochemistry, single cell RNA-sequencing, bioinformatics.
You have good communication skills and you are fully proficient in spoken and written English. Previous work experience in international environments is considered advantageous.
Please contact Gesine.Paul-Visse@med.lu.se. Starting date can be discussed.