Job ID: 100367

Two postdoc positions in neurotrophic factors, plasticity and drug action

Position: Post-doctoral Position

Deadline: 31 January 2023

City: Helsinki

Country: Finland

Institution: University of Helsinki

Department: Neuroscience Center / HiLIFE


Research group of Eero Castrén ( is looking for enthusiastic young scientist to investigate the role of neuronal plasticity and neurotrophic factors in the mechanisms of drug action, especially the antidepressant drugs. We are working in the Neuroscience Center of the University of Helsinki (, with excellent facilities and environment.

We have recently discovered that different antidepressant drugs directly bind to the BDNF receptor TrkB (Casarotto et al., Cell, 2021). This project will build on these findings and search for novel potential antidepressants that are selective to TrkB as well as on the mechanisms of action on TrkB and its downstream signaling, including neuronal responses and behavioral effects in mice.

The successful candidate should have a doctoral degree and preferentially prior postdoctoral experience, with a strong expertise in cellular and molecular biology, prior experience in neuroscience and mouse behavioral testing is an advantage.  The candidate is expected to do research, supervise doctoral students, and participate in the teaching program of the Neuroscience Center.  Salary is negotiable and based on experience.

Please send application, CV, list of publications and 3 references by January 31st, 2023, to:

Eero Castrén

Phone: +358-50-520 7974